ISCO3 documents are recommendations which may become source of guiding and reference to all those who practice ozone therapy. However it is up to each ozone therapist to follow or not the recommendations issued by ISCO3.

All documents are online and of free access. The only exception is the Madrid Declaration on Ozone Therapy.

All documents are in English and a few of them have been translated into Spanish.

If you want to contribute in translating a paper from English into your mother tongue please previously contact:

Copyright (©). All rights reserved (©)by ISCO3

ISCO3 Official Documents

Medicina Humana


Ozone in SARS-CoV-2 / COVID-19.

Potential use of ozone in SARS-CoV-2 / COVID-19.

Scientific Paper Approved by ISCO3 on March 13, 2020.

In this document, ISCO3  (International Scientific Committee of Ozone Therapy)    has taken into account that WHO has officially recognized that “currently, there are no vaccines or specific pharmaceutical treatments available for COVID-19.” So this paper offers a contribution to fight the coronavirus proposing the potential use of ozone therapy, as a complementary therapy, exclusively based on scientific available data as is explained in detail in this paper.

You can consult the document in the following languages (the only official version of the document is the one published in English):

1. ISCO3 Global reference document


2. ISCO3 Papers of Good Clinical Practice

enDefinitions of Terms in Ozone Therapy. October 16, 2019

enDefinizioni dei termini in ozonoterapia [Definitions of Terms in Ozone Therapy]16 ottobre 2019 .

enDefinitionen und Begriffe in der Ozone-therapie [Definitions of Terms in Ozone Therapy]. 16th Oktober, 2019.

enDental Ozone Therapy, the State of the ArtApril 23, 2018

enTreatment of Tonsillitis with OzoneOctober 8, 2017.

esTratamiento de la amigdalitis con ozono. October 8, 2017.

enNon-recommended routes of application in ozone therapy. September 5, 2017.

esVías de aplicación no recomendadas en ozono terapia. 5 septiembre 2017.

IT-Italy-Flag-iconPercorsi di applicazione non raccomandati nella terapia con ozono. 5 settembre 2017.

enParavertebral Ozone Therapy. January 1, 2017

enExtracorporeal blood oxygenation-ozonation (EBOO). . November 30, 2016

esOxigenación-Ozonización Extracorpórea de la Sangre (OOES). 30 noviembre 2016.

IT-Italy-Flag-iconOssigeno-ozonizzazione extracorporea del sangue (EBOO). 3 ottobre 2016.

enMajor Autohemotherapy. October 2, 2016.

esAutohemoterapia Mayor. 2 octubre 2016.

IT-Italy-Flag-icon   Grande Autoemoterapia. 2 ottobre 2016

enOzone micro doses in acupuncture reflexology and trigger points. August 28, 2016

enVaginal insufflation of an ozone-oxygen mixture (VIO3O2M). June 13, 2016.

enMinor AutohemotherapyMarch 31, 2016.

enRectal Insufflation. February 5, 2016.

esInsuflación rectal. 5 febrero 2016.

IT-Italy-Flag-iconInsufflazioni rettali. 5 febbraio 2016.

enSubcutaneous infiltration of hands (Glove technic). February 3, 2016.

3. ISCO3 Clinical Applications

4. ISCO3 Analytical Laboratories

5. ISCO3 Reference Documents for Recognition and/or Regularization of the Ozone Therapy by the Health Authorities

Both papers are medical and legal tools that should be used in two ways: by those interested in ozone therapy to increase their knowledge and strengthen their practice; and by national associations of ozone therapy in getting soon rather than later the legal recognition of the therapy by health authorities.

6. ISCO3 Medical and technical requests for the use of ozone therapy generators

7. ISCO3 Pioneers of the Modern Ozone Therapy

8. ISCO3 Forms & Templates


10. ISCO3 Online Ozone Therapy International Library

ISCO3 has developed and keep updated a library of all published and presented papers on ozone therapy. It contains more than 2000 records: indexed and not indexed papers, books, thesis, historical papers and other documents. The data base is growing-up day by day. Access to the library.

This specialized website is addressed exclusively to professionals involved in the health sector and specifically in the ozone therapy. In addition all the information provided here, does not substitute the need for a personalized medical evaluation, carried out by a health professional.